SHOULD TITRES BE CHECKED?
Persons who have had shingles in the last year are considered immune.
This vaccine is no longer available and has been replaced by the non-live herpes zoster (Shingrix®) vaccine.
BEFORE INITIATION OF IMMUNE SUPPRESSION
Not recommended. Use inactivated vaccine.
WHAT TO DO IF ALREADY IMMUNOSUPPRESSED
(ON ANTI-TNF OR IMMUNOMODULATOR)
Not recommended. Use inactivated vaccine.
Note: The non-live herpes zoster (Shingrix®) vaccine is suggested for all IBD patients who are immunosuppressed age 18 years and older, and strongly recommended for all IBD patients age 50 and older, whether immunosuppressed or not.
CHECK TITRE BEFORE VACCINATION?
Not applicable
RECCOMENDATIONS / COMMENTS
Contraindicated (use inactivated vaccine)
WHAT TO DO IF ALREADY IMMUNOSUPPRESSED
(ON ANTI-TNF OR IMMUNOMODULATOR)
Contraindicated.
VACCINE
- Lyophilized (freeze-dried) vaccine – Smallpox Vaccine (dried) (Sanofi Pasteur Ltd.)
- Frozen liquid formulation vaccine – Smallpox Vaccine (frozen-liquid) (Sanofi Pasteur Ltd).
CHECK TITRE BEFORE VACCINATION?
Naturally occurring smallpox has been eradicated worldwide and smallpox vaccination is associated with the risk of significant morbidity and even mortality. The overall risk-benefit analysis supports the recommendation to not routinely immunize the general Canadian population against smallpox. As a result, smallpox vaccination is highly restricted.
BEFORE INITIATION OF IMMUNE SUPPRESSION
WHAT TO DO IF ALREADY IMMUNOSUPPRESSED
(ON ANTI-TNF OR IMMUNOMODULATOR)
Not recommended