TB screening should be considered.
IV infusion and SC injection
Infusion centre
Induction: 300 mg IV wk 0, wk 2, wk 6, then maintenance 300 mg every 8 wks OR following at least 2 IV infusions, 108 mg SC every 2 wks†
1–2 hrs
Patients should be monitored for any new onset or worsening of neurological signs and symptoms
Liver enzymes – transaminases and bilirubin.