PRE-TESTING AND VACCINATION

For more detailed information on vaccinations, please see the CANIBD Vaccination Guide

Chest X-ray
TB skin test
Blood work (baseline CBC, renal and liver function, HBV)

Ensure all immunizations are current.
Wait at least four weeks to start following administration of live vaccination.
Pneumococcal vaccination recommended for adult patients.
Recommend vaccinations: HAV, HBV, HPV, and Tdap
Refer to CANIBD Vaccination Guidelines for further information.10

Use with caution in patients with chronic or recurrent infection.

METHOD OF ADMINISTRATION

SC injection

LOCATION

Home
Infusion centre is also available

DOSING

Induction:
160 mg, 80 mg,
40 mg, wk 0, wk 2, wk 4,

then maintenance
40 mg every 2 wks*

Pediatric Dosing:
13 to 17 years of age

≥ 40 kg: 160 mg at Week 0, 80 mg at Week 2. Maintenance dose regimen is 20 mg every other week beginning at Week 4.

For pediatric patients who experience a disease flare or non-response, dose escalation to 40 mg every other week may be considered

TIME REQUIRED

<15 min

ROUTINE MONITORING

Annual cervical cancer screening – pap test
Annual skin exam – skin malignancies
Influenza vaccine recommended
May consider therapeutic drug monitoring (TDM) if available
Screening for osteoporosis with bone mineral density testing periodically after diagnosis